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Berk M, Dean O, Cotton SM, Gama CS, Kapczinski F, Fernandes BS, Kohlmann K, Jeavons S, Hewitt K, Allwang C, Cobb H, Bush AI, Schapkaitz I, Dodd S, Malhi GS (2011) The efficacy of N-acetylcysteine as an adjunctive treatment in bipolar depression: an open label trial

This approach mitigates metabolic slowdown, improves adherence, and supports sustainable weight loss

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Second, the glutathione S-transferases (GSTs) catalyze the conjugation of the thiol group of GSH to a vast array of electrophilic xenobiotics and endogenous metabolites